In 2025, skin biostimulation has become one of the most in-demand trends in aesthetic medicine — and for good reason. As more people move away from overfilled, artificial-looking results, biostimulation offers a subtle, natural way to restore skin health from within. But how do you know if it’s the right time to start?



At Mesglo Aesthetic Clinic Marylebone London, we specialise in regenerative, science-backed skin treatments that improve skin tone, texture, elasticity, and long-term radiance. In this article, we’ll help you understand what biostimulation is, who it’s for, and how to tell if your skin is ready for this next-level rejuvenation approach.



What Is Skin Biostimulation?



Biostimulation refers to treatments that stimulate your skin’s own regenerative processes, encouraging it to produce more collagen, elastin, and hyaluronic acid naturally — without relying on synthetic volume.



Unlike dermal fillers or neurotoxins, biostimulatory treatments rebuild skin quality at a cellular level and improve its long-term health and resilience.



Popular Biostimulatory Treatments at Mesglo:



✨ Polynucleotides – Repair damaged tissue, improve elasticity and hydration.✨ Exosomes – Cellular messengers that signal repair and regeneration.✨ Profhilo® / Seventy Hyal – High-purity HA that hydrates and stimulates collagen.✨ Microneedling + Growth Factors – Micro-injury + regenerative ingredients to trigger repair.



5 Signs You’re Ready for Skin Biostimulation



1. Your Skin Feels Dull or Dehydrated — Even After Moisturising



If topical products aren't doing enough and your skin still feels tight, flaky, or flat, this could be a sign that the deeper dermal layers need support. Biostimulation improves internal hydration and cellular renewal, giving you that lit-from-within glow.



2. You’re Starting to Notice Fine Lines or Loss of Firmness



Early signs of ageing — like lines around the mouth, crow’s feet, or skin that no longer ‘snaps back’ — are ideal for biostimulation. https://mesglolondon.co.uk/are-you-ready-for-skin-biostimulation-heres-how-to-tell/