Under‑eye hollows and dark circles are among the most common cosmetic concerns. Two of the most popular professional treatments are hyaluronic‑acid tear‑trough fillers and the newer polynucleotide therapy marketed as Lumi Eyes. Each treatment has distinct mechanisms, benefits and risks. This comparative guide will help you decide which option may suit your needs and why consulting an experienced practitioner is essential.

How do the treatments work?

Hyaluronic‑acid tear‑trough fillers: Dermal fillers for the tear trough contain hyaluronic acid (HA), a naturally occurring sugar molecule that attracts water. When injected into the hollow, HA restores lost volume, smooths the transition between the lower lid and the cheek and reduces shadows. Current fillers are produced by bacterial fermentation and chemically cross‑linked to reduce allergic reactions⁹. The effect is immediate and can last 6–18 months¹⁰. Fillers are best suited for structural hollows rather than pigmentation.

Lumi Eyes polynucleotide therapy: Lumi Eyes is a mesotherapy treatment that uses purified polynucleotides (long DNA fragments derived from salmon) with hyaluronic acid and antioxidants¹³. Unlike volumising fillers, polynucleotides act as tissue stimulators. They promote fibroblast proliferation, extracellular matrix synthesis, collagen production and angiogenesis⁴. Clinical trials indicate that polynucleotide injections improve skin elasticity, hydration and wrinkle depth and may even outperform hyaluronic‑acid fillers in reducing wrinkle depth and improving skin texture¹². Because results depend on tissue regeneration, multiple sessions are usually required. https://mesglolondon.co.uk/?p=4295